ENDOSCAPE at Conferences

International ENDOSCAPE Symposium

Venue: Berlin
Date: 08.-09.09.2022

Harnack-Haus, Tagungsstätte der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
Ihnestraße 16-20, 14195 Berlin

registration and poster/abstract submission here

Day 1 | 11:30 – 19:45

o Session 1: Gene Therapy – Where We Stand Today

  • Non-viral gene therapy at a glance - Kazunori Kataoka, Tokyo
  • Gene therapy in monogenetic diseases - Company presentation
  • Suicide genes in cancer therapy - Company presentation
  • Participant presentations

o Session 2: Endosomal Escape – The Strategies

  • Strategies for intracellular delivery and endosomal escape - Vladimir P. Torchilin, Boston
  • Photochemically-induced release - Pål Kristian Selbo, Oslo
  • Intracellular drug delivery - Company presentation
  • Glycosylated triterpenoids as endosomal escape enhancers - ENDOSCAPE-Partner FUB
  • Cell penetrating peptides - Jean-Philippe Pellois, Texas

o Poster session

Day 2 | 08:15 – 18:30

o Session 3: Carriers of Endosomal Escape Enhancers and Genes

  • Design of efficient intracellular delivery vehicles - Jan van Hest, Eindhoven
  • Scaffolds to carry endosomal escape enhancers and targeting ligands, and to polyplex effector genes: PAMAMs, peptides and DNA - ENDOSCAPE-Partners CHARITE, FUB, UNITOV, USC
  • Nanocarriers - Company presentation
  • Chemical evolution refining intercellular mRNA, protein and Cas9/sgRNA delivery - Ernst Wagner, München

o Session 4: Endosomal Escape – What Happens?

  • Intracellular routing of targeted payloads - Inge Zuhorn, Groningen
  • Mechanisms of endosomal trafficking and escape by SO1861 - ENDOSCAPE-Partner MPG
  • Efficacy of endosomal escape enhancers in vitro and ex vivo - ENDOSCAPE-Partner UNIFE, SAPREME, CHARITE
  • Endosomal escape by photochemical internalization - Company presentation
  • Participant presentation

o Poster session

o Session 5: GMP Production and Market

  • Controlled production of endosomal escape enhancers in plants - ENDOSCAPE-Partners Fraunhofer and EXSY
  • Gene discovery and synthetic biology for biosynthesis of endosomal escape enhancers in engineered plant cultures - ENDOSCAPE Partner VIB
  • Gene therapy from bench to bedside - Company presentation
  • Innovative solutions for GMP production of biopharmaceuticals - Company presentation
  • Cost-of-goods analysis of the ENDOSCAPE technology - ENDOSCAPE-Partner UNIBAS
  • Cost-effectiveness analysis of potential gene therapies for Hemophilia B based on ENDOSCAPE - ENDOSCAPE-Partner UNIBAS
  • Participant presentations

o Session 6: Gene Therapy – Clinical Applications and Future Perspectives

  • Gene-based nanomedicines for cancer therapy and brain delivery - Christine Dufès, Glasgow
  • Transplantation of genetically modified hematopoietic stem cells - Fulvio Mavilio, Modena
  • Gene therapy of Hemophilia - Antonia Follenzi, Novara
  • Current status of non-viral gene therapy: The ENDOSCAPE symposium at a glance - ENDOSCAPE-Partners

Company presentations depending on registrations. If applicable, replacement by selected poster contributions as short presentations.

ENDOSCAPE partner presentations:
CHARITE: Charité – Universitätsmedizin Berlin
FUB: Freie Universität Berlin
UNITOV: The University of Rome Tor Vergata
USC: Universidade de Santiago de Compostela
MPG: Max-Planck-Gesellschaft zur Förderung der Wissenschaften
UNIFE: The Universita degli Studi di Ferrara
SAPREME: Sapreme Technologies B.V.
VIB: Vlaams Instituut Biotechnologie
Fraunhofer: Fraunhofer - Gesellschaft zur Förderung der Angewandten Forschung e.V.
UNIBAS: Universität Basel

ENDOSCAPE Publications